Molecular hydrogen is being studied intensely in Asia by Scientists, MDs and PhDs. There are over 600 studies published. Hydrogen helps with over 166 human identified conditions. It has been shown to be safe for everyone, as the body makes it naturally every day in the intestines. The clinical studies are mostly reported from Japan, Korea and China, the three countries that are actively funding molecular hydrogen research.
Hydrogen gas has no cytotoxicity, even at high concentrations. The safety of H2 for humans is demonstrated by its application in Hydreliox, an exotic breathing gas with a mixture of 49% H2, 50% helium and 1% O2, which is used to prevent decompression sickness and nitrogen narcosis during very deep technical diving. ( 1 ) With Hydreliox in their tanks, scuba divers can safely pursue diving depths of up to four hundred feet.
Hydrogen water has lots of not understood properties. The absolute tiniest concentration dissolved in water has still statistical significant effects. Notably, H2 concentrations as low as 0.08 ppm exhibited nearly the same effects as saturated Hydrogen water with (1.5 ppm). Therefore, the amount of administered H2 seems to be independent of the magnitude of effects in many cases.
We need to know how to optimize H2 dose, timing, and delivery methods. Nevertheless, for H2 treatment, promising applications are emerging for many human diseases, and personalized treatments for patients are a therapeutic goal. Thus, appropriately designed for large-scale, prospective clinical studies are warranted.
The positive effects of H2 have been observed in practically all organs covering 31 disease categories that can be subdivided into 166 disease models, human diseases, treatment-associated pathologies, and pathophysiological conditions of plants. A predominance of oxidative stress-mediated diseases and inflammatory diseases has been observed.
A successful drug has to be easily available, diffuse rapidly, act on multiple pathological intertwined mechanisms and have few side effects. Hydrogen is all that.
These publications are very instructive because they summarize all current and past studies on Hydrogen.
2016: Dr. Gart L. Nicholson reports on 338 publications studying the benefits of molecular hydrogen at scirp.org:
Click any of the links above and search in the opening document for the medical term you are interested in.
Tip: You will find bracketed numbers like this  all over in these documents. Clicking them will show the url of the original publication at the bottom of the document.
The most common argument of critics is that the scientific studies are done only in vitro and with animals. Nothing could be further from the truth. There are each year more studies and trials done with humans. A revolution in remedial and preventive medicine is coming.
60 completed and published human studies [ 15 ]
Another 25 registered, but still running human studies [ 16 ]
This hydrogen inhalation therapy is the first full-scale clinical trial in the world to confirm the effectiveness performed by the Japanese Ministry of Health, Labor and Welfare after being certified as advanced medical technology. A multi institution, double blind, human clinical trial: Efficacy of inhaled hydrogen gas therapy for patients after out-of-hospital cardiac arrest  [Google translation]
Tip: Sometimes, when the content is just the abstract, you have to look for the full article at the bottom of the opening page.
The scope of all research done since 2007 covers nearly every disease known.
Reviewing the three lists below and considering the non-toxicity and benign nature of Hydrogen, it is possible to experiment in any direction. The trend in all reports is towards homeostasis.
A collection of general articles, studies and publications.
Bipolar - Schizophrenia
Excessive production of free radicals
Gastric injury, ulcers, alcohol damage
A collection of animal studies and publications.
Gastric injury, ulcers, alcohol damage
Inflammatory Bowel Disease
A collection of the human studies and publications. There are 25 more to be completed in the next years.
Confirmation of hydrogen in breath
Search and review the nih.gov: HTML
Search and review biomedcentral.com: HTML
General Studies about Hydrogen.
The reference links to hydrogen information
I guess everyone gets the idea that for a lot of patients, hydrogen could better their lives.